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Immunogenicity in Rabbits of HIV-1 SOSIP Trimers from Clades A, B, and C, Given Individually, Sequentially, or in Combination

Recombinant soluble HIV-1 envelope glycoprotein (Env) SOSIP trimers are a design platform for inducing broadly neutralizing antibodies (bNAbs) by vaccination. To date, these and alternative designs of native-like trimers, given singly or in pairs, have not induced bNAbs in test animals such as rabbi...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Torrents de la Peña, Alba, de Taeye, Steven W., Sliepen, Kwinten, LaBranche, Celia C., Burger, Judith A., Schermer, Edith E., Montefiori, David C., Moore, John P., Klasse, Per Johan, Sanders, Rogier W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874403/
https://ncbi.nlm.nih.gov/pubmed/29367243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01957-17
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