Human Circulating PD-1(+)CXCR3(−)CXCR5(+) Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

The vast majority of currently licensed human vaccines work on the basis of long-term protective antibody responses. It is now conceivable that an antibody-dependent HIV vaccine might be possible, given the discovery of HIV broadly neutralizing antibodies (bnAbs) in some HIV-infected individuals. Ho...

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Autori principali: Locci, Michela, Havenar-Daughton, Colin, Landais, Elise, Wu, Jennifer, Kroenke, Mark A., Arlehamn, Cecilia L., Su, Laura F., Cubas, Rafael, Davis, Mark M., Sette, Alessandro, Haddad, Elias K., Poignard, Pascal, Crotty, Shane
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996844/
https://ncbi.nlm.nih.gov/pubmed/24035365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.031
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