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IL-12 and type-I IFN synergize for IFN-γ production by CD4 T cells, while neither are required for IFN-γ production by CD8 T cells after Listeria monocytogenes infection
Differentiation of antigen specific T cells into IFN-γ producers is essential for protective immunity to intracellular pathogens. In addition to stimulation through the TCR and costimulatory molecules, IFN-γ production is thought to require other inflammatory cytokines. Two such inflammatory cytokin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626161/ https://ncbi.nlm.nih.gov/pubmed/17372008 |
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