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A critical role for phospholipase C in protective immunity conferred by Listeriolysin O-deficient Listeria monocytogenes

Attenuated recombinant Listeria monocytogenes (Lm) strains are a promising class of vaccine vectors that trigger protective antigen-specific CD8 T cells. Listeriolysin O (LLO) is an important Lm virulence determinant allowing the bacterium to escape from the endocytic vacuole into the cell cytoplasm...

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Detalhes bibliográficos
Main Authors: Orgun, Nural N., Way, Sing Sing
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276143/
https://ncbi.nlm.nih.gov/pubmed/17888620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2007.08.002
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