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IL-12 and type-I IFN synergize for IFN-γ production by CD4 T cells, while neither are required for IFN-γ production by CD8 T cells after Listeria monocytogenes infection

Differentiation of antigen specific T cells into IFN-γ producers is essential for protective immunity to intracellular pathogens. In addition to stimulation through the TCR and costimulatory molecules, IFN-γ production is thought to require other inflammatory cytokines. Two such inflammatory cytokin...

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Bibliografske podrobnosti
Main Authors: Way, Sing Sing, Havenar-Daughton, Colin, Kolumam, Ganesh A., Orgun, Nural N., Murali-Krishna, Kaja
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626161/
https://ncbi.nlm.nih.gov/pubmed/17372008
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