Prediction of peptides binding to MHC class I and II alleles by temporal motif mining

Por Meydan, Cem, Otu, Hasan H, Sezerman, Osman Uğur
Publicado em 2013

Growth Kinetics, Carbon Isotope Fractionation, and Gene Expression in the Hyperthermophile Methanocaldococcus jannaschii during Hydrogen-Limited Growth and Interspecies Hydrogen Tr...

Por Topçuoğlu, Begüm D., Meydan, Cem, Nguyen, Tran B., Lang, Susan Q., Holden, James F.
Publicado no Appl Environ Microbiol (2019)

Testing robustness of relative complexity measure method constructing robust phylogenetic trees for Galanthus L. Using the relative complexity measure

Por Bakış, Yasin, Otu, Hasan H, Taşçı, Nivart, Meydan, Cem, Bilgin, Neş’e, Yüzbaşıoğlu, Sırrı, Sezerman, O Uğur
Publicado em 2013

Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome

Por Linder, Bastian, Grozhik, Anya V., Olarerin-George, Anthony O., Meydan, Cem, Mason, Christopher E., Jaffrey, Samie R.
Publicado no Nat Methods (2015)

rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline

Por Jain, Devanshi, Meydan, Cem, Lange, Julian, Claeys Bouuaert, Corentin, Lailler, Nathalie, Mason, Christopher E., Anderson, Kathryn V., Keeney, Scott
Publicado no PLoS Genet (2017)

ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2

Por Jain, Devanshi, Puno, M Rhyan, Meydan, Cem, Lailler, Nathalie, Mason, Christopher E, Lima, Christopher D, Anderson, Kathryn V, Keeney, Scott
Publicado no eLife (2018)

Target-Independent Prediction of Drug Synergies Using Only Drug Lipophilicity

Por Yilancioglu, Kaan, Weinstein, Zohar B., Meydan, Cem, Akhmetov, Azat, Toprak, Isil, Durmaz, Arda, Iossifov, Ivan, Kazan, Hilal, Roth, Frederick P., Cokol, Murat
Publicado em 2014

Improved gastrointestinal health for irritable bowel syndrome with metagenome-guided interventions

Por Meydan, Cem, Afshinnekoo, Ebrahim, Rickard, Nate, Daniels, Guy, Kunces, Laura, Hardy, Theresa, Lili, Loukia, Pesce, Sarah, Jacobson, Paul, Mason, Christopher E, Dudley, Joel, Zhang, Bodi
Publicado no Precis Clin Med (2020)

Identification of Immune complement function as a determinant of adverse SARS-CoV-2 infection outcome

Por Ramlall, Vijendra, Thangaraj, Phyllis M., Meydan, Cem, Foox, Jonathan, Butler, Daniel, May, Ben, De Freitas, Jessica K., Glicksberg, Benjamin S., Mason, Christopher E., Tatonetti, Nicholas P., Shapira, Sagi D.
Publicado no medRxiv (2020)

Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response

Por Agirre, Xabier, Meydan, Cem, Jiang, Yanwen, Garate, Leire, Doane, Ashley S., Li, Zhuoning, Verma, Akanksha, Paiva, Bruno, Martín-Subero, José I., Elemento, Olivier, Mason, Christopher E., Prosper, Felipe, Melnick, Ari
Publicado no Nat Commun (2019)

Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells

Por Kunimoto, Hiroyoshi, McKenney, Anna Sophia, Meydan, Cem, Shank, Kaitlyn, Nazir, Abbas, Rapaport, Franck, Durham, Benjamin, Garrett-Bakelman, Francine E., Pronier, Elodie, Shih, Alan H., Melnick, Ari, Chaudhuri, Jayanta, Levine, Ross L.
Publicado no Blood (2017)

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity

Por Kunimoto, Hiroyoshi, Meydan, Cem, Nazir, Abbas, Whitfield, Justin, Shank, Kaitlyn, Rapaport, Franck, Maher, Rebecca, Pronier, Elodie, Meyer, Sara C., Garrett-Bakelman, Francine E., Tallman, Martin, Melnick, Ari, Levine, Ross L., Shih, Alan H.
Publicado no Cancer Cell (2017)

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

Por Viny, Aaron D., Ott, Christopher J., Spitzer, Barbara, Rivas, Martin, Meydan, Cem, Papalexi, Efthymia, Yelin, Dana, Shank, Kaitlyn, Reyes, Jaime, Chiu, April, Romin, Yevgeniy, Boyko, Vitaly, Thota, Swapna, Maciejewski, Jaroslaw P., Melnick, Ari, Bradner, James E., Levine, Ross L.
Publicado no J Exp Med (2015)

Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia

Por Shih, Alan H, Meydan, Cem, Shank, Kaitlyn, Garrett-Bakelman, Francine E, Ward, Patrick S, Intlekofer, Andrew, Nazir, Abbas, Stein, Eytan, Knapp, Kristina, Glass, Jacob, Travins, Jeremy, Straley, Kim, Gliser, Camelia, Mason, Chris, Yen, Katharine, Thompson, Craig B, Melnick, Ari, Levine, Ross L
Publicado no Cancer Discov (2017)

Histone Demethylase LSD1 is required for Germinal Center formation and BCL6-driven lymphomagenesis

Por Hatzi, Katerina, Geng, Huimin, Doane, Ashley S., Meydan, Cem, LaRiviere, Reed, Cardenas, Mariano, Duy, Cihangir, Shen, Hao, Vidal, Maria Nieves Calvo, Baslan, Timour, Mohammad, Helai P., Kruger, Ryan G., Shaknovich, Rita, Haberman, Ann M., Inghirami, Giorgio, Lowe, Scott W., Melnick, Ari M.
Publicado no Nat Immunol (2018)

MUTANT EZH2 INDUCES A PRE-MALIGNANT LYMPHOMA NICHE BY REPROGRAMMING THE IMMUNE RESPONSE

Por Béguelin, Wendy, Teater, Matt, Meydan, Cem, Hoehn, Kenneth B., Phillip, Jude M., Soshnev, Alexey A., Venturutti, Leandro, Rivas, Martín A., Calvo-Fernández, María T., Gutierrez, Johana, Camarillo, Jeannie M., Takata, Katsuyoshi, Tarte, Karin, Kelleher, Neil L., Steidl, Christian, Mason, Christopher E., Elemento, Olivier, Allis, C. David, Kleinstein, Steven H., Melnick, Ari M.
Publicado no Cancer Cell (2020)

Epigenetic identity in AML depends on disruption of non-promoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers

Por Glass, Jacob L., Hassane, Duane, Wouters, Bas J., Kunimoto, Hiroyoshi, Avellino, Roberto, Garrett-Bakelman, Francine E., Guryanova, Olga A., Bowman, Robert, Redlich, Shira, Intlekofer, Andrew M., Meydan, Cem, Qin, Tingting, Fall, Mame, Alonso, Alicia, Guzman, Monica L., Valk, Peter J.M., Thompson, Craig B., Levine, Ross, Elemento, Olivier, Delwel, Ruud, Melnick, Ari, Figueroa, Maria E.
Publicado no Cancer Discov (2017)

Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

Por Shih, Alan H., Jiang, Yanwen, Meydan, Cem, Shank, Kaitlyn, Pandey, Suveg, Barreyro, Laura, Antony-Debre, Ileana, Viale, Agnes, Socci, Nicholas, Sun, Yongming, Robertson, Alexander, Cavatore, Magali, de Stanchina, Elisa, Hricik, Todd, Rapaport, Franck, Woods, Brittany, Wei, Chen, Hatlen, Megan, Baljevic, Muhamed, Nimer, Stephen D., Tallman, Martin, Paietta, Elisabeth, Cimmino, Luisa, Aifantis, Iannis, Steidl, Ulrich, Mason, Chris, Melnick, Ari, Levine, Ross L.
Publicado no Cancer Cell (2015)

Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML

Por Duy, Cihangir, Teater, Matt, Garrett-Bakelman, Francine E., Lee, Tak C., Meydan, Cem, Glass, Jacob L., Li, Meng, Hellmuth, Johannes C., Mohammad, Helai P., Smitheman, Kimberly N., Shih, Alan H., Abdel-Wahab, Omar, Tallman, Martin S., Guzman, Monica L., Muench, David, Leighton Grimes, H., Roboz, Gail J., Kruger, Ryan G., Creasy, Caretha L., Paietta, Elisabeth M., Levine, Ross L., Carroll, Martin, Melnick, Ari M.
Publicado no Cancer Discov (2019)

CREBBP inactivation promotes the development of HDAC3 dependent lymphomas

Por Jiang, Yanwen, Ortega-Molina, Ana, Geng, Huimin, Ying, Hsia-Yuan, Hatzi, Katerina, Parsa, Sara, McNally, Dylan, Wang, Ling, Doane, Ashley S., Ena, Xabier Agirre, Teater, Matt, Meydan, Cem, Li, Zhuoning, Poloway, David, Wang, Shenqiu, Ennishi, Daisuke, Scott, David W., Stengel, Kristy R., Kranz, Janice E., Holson, Edward, Sharma, Sneh, Young, James W., Chu, Chi-Shuen, Roeder, Robert G., Shaknovich, Rita, Hiebert, Scott W., Gascoyne, Randy D., Tam, Wayne, Elemento, Olivier, Wendel, Hans-Guido, Melnick, Ari M.
Publicado no Cancer Discov (2016)