Loading...

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

Cohesin complex members have recently been identified as putative tumor suppressors in hematologic and epithelial malignancies. The cohesin complex guides chromosome segregation; however, cohesin mutant leukemias do not show genomic instability. We hypothesized that reduced cohesin function alters c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Viny, Aaron D., Ott, Christopher J., Spitzer, Barbara, Rivas, Martin, Meydan, Cem, Papalexi, Efthymia, Yelin, Dana, Shank, Kaitlyn, Reyes, Jaime, Chiu, April, Romin, Yevgeniy, Boyko, Vitaly, Thota, Swapna, Maciejewski, Jaroslaw P., Melnick, Ari, Bradner, James E., Levine, Ross L.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612085/
https://ncbi.nlm.nih.gov/pubmed/26438361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151317
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!