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Cohesin mutations in myeloid malignancies made simple

PURPOSE OF REVIEW: Recurrent loss of function mutations within genes of the cohesin complex have been identified in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). STAG2 is the most commonly mutated cohesin member in AML as well as solid tumors. STAG2 is recurrently, mutated in Ewin...

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Detalhes bibliográficos
Publicado no:Curr Opin Hematol
Main Authors: Viny, Aaron D., Levine, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601335/
https://ncbi.nlm.nih.gov/pubmed/29278534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000405
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