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Cohesin mutations in myeloid malignancies made simple
PURPOSE OF REVIEW: Recurrent loss of function mutations within genes of the cohesin complex have been identified in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). STAG2 is the most commonly mutated cohesin member in AML as well as solid tumors. STAG2 is recurrently, mutated in Ewin...
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| Publicado en: | Curr Opin Hematol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601335/ https://ncbi.nlm.nih.gov/pubmed/29278534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000405 |
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