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Cohesin mutations in myeloid malignancies: underlying mechanisms

Recently, whole genome sequencing approaches have pinpointed mutations in genes that were previously not associated with cancer. For Acute Myeloid Leukaemia (AML), and other myeloid disorders, these approaches revealed a high prevalence of mutations in genes encoding the chromosome cohesion complex,...

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Détails bibliographiques
Auteurs principaux: Leeke, Bryony, Marsman, Judith, O’Sullivan, Justin M, Horsfield, Julia A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046106/
https://ncbi.nlm.nih.gov/pubmed/24904756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-13
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