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Cohesin mutations in myeloid malignancies: underlying mechanisms

Recently, whole genome sequencing approaches have pinpointed mutations in genes that were previously not associated with cancer. For Acute Myeloid Leukaemia (AML), and other myeloid disorders, these approaches revealed a high prevalence of mutations in genes encoding the chromosome cohesion complex,...

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Autori principali: Leeke, Bryony, Marsman, Judith, O’Sullivan, Justin M, Horsfield, Julia A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046106/
https://ncbi.nlm.nih.gov/pubmed/24904756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-13
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