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Cohesin mutations in myeloid malignancies: underlying mechanisms

Recently, whole genome sequencing approaches have pinpointed mutations in genes that were previously not associated with cancer. For Acute Myeloid Leukaemia (AML), and other myeloid disorders, these approaches revealed a high prevalence of mutations in genes encoding the chromosome cohesion complex,...

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Main Authors: Leeke, Bryony, Marsman, Judith, O’Sullivan, Justin M, Horsfield, Julia A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046106/
https://ncbi.nlm.nih.gov/pubmed/24904756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-13
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