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Cohesin mutations in myeloid malignancies: underlying mechanisms

Recently, whole genome sequencing approaches have pinpointed mutations in genes that were previously not associated with cancer. For Acute Myeloid Leukaemia (AML), and other myeloid disorders, these approaches revealed a high prevalence of mutations in genes encoding the chromosome cohesion complex,...

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Bibliographic Details
Main Authors: Leeke, Bryony, Marsman, Judith, O’Sullivan, Justin M, Horsfield, Julia A
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046106/
https://ncbi.nlm.nih.gov/pubmed/24904756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-13
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