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Low tolerance for transcriptional variation at cohesin genes is accompanied by functional links to disease-relevant pathways
Background: The cohesin complex plays an essential role in genome organisation and cell division. A full complement of the cohesin complex and its regulators is important for normal development, since heterozygous mutations in genes encoding these components can be sufficient to produce a disease ph...
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| Udgivet i: | J Med Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMJ Publishing Group
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8327319/ https://ncbi.nlm.nih.gov/pubmed/32917770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2020-107095 |
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