rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline

Transcriptional silencing by heritable cytosine-5 methylation is an ancient strategy to repress transposable elements. It was previously thought that mammals possess four DNA methyltransferase paralogs—Dnmt1, Dnmt3a, Dnmt3b and Dnmt3l—that establish and maintain cytosine-5 methylation. Here we ident...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Jain, Devanshi, Meydan, Cem, Lange, Julian, Claeys Bouuaert, Corentin, Lailler, Nathalie, Mason, Christopher E., Anderson, Kathryn V., Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607212/
https://ncbi.nlm.nih.gov/pubmed/28854222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006964
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados