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Transposition of the human Hsmar1 transposon: rate-limiting steps and the importance of the flanking TA dinucleotide in second strand cleavage

Hsmar1 is a member of the mariner family of DNA transposons. Although widespread in nature, their molecular mechanism remains obscure. Many other cut-and-paste elements use a hairpin intermediate to cleave the two strands of DNA at each transposon end. However, this intermediate is absent in mariner...

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Sonraí Bibleagrafaíochta
Main Authors: Claeys Bouuaert, Corentin, Chalmers, Ronald
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800235/
https://ncbi.nlm.nih.gov/pubmed/19858101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp891
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