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Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target
Hsmar1 is a member of the Tc1-mariner superfamily of DNA transposons. These elements mobilize within the genome of their host by a cut-and-paste mechanism. We have exploited the in vitro reaction provided by Hsmar1 to investigate the effect of DNA supercoiling on transposon integration. We found tha...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544897/ https://ncbi.nlm.nih.gov/pubmed/23341977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053690 |
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