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Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target

Hsmar1 is a member of the Tc1-mariner superfamily of DNA transposons. These elements mobilize within the genome of their host by a cut-and-paste mechanism. We have exploited the in vitro reaction provided by Hsmar1 to investigate the effect of DNA supercoiling on transposon integration. We found tha...

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Main Authors: Claeys Bouuaert, Corentin, Chalmers, Ronald
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544897/
https://ncbi.nlm.nih.gov/pubmed/23341977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053690
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