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Target-Independent Prediction of Drug Synergies Using Only Drug Lipophilicity
[Image: see text] Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency to exhibit drug interaction has not been systematically studie...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144720/ https://ncbi.nlm.nih.gov/pubmed/25026390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500276x |
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