Target-Independent Prediction of Drug Synergies Using Only Drug Lipophilicity

[Image: see text] Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency to exhibit drug interaction has not been systematically studie...

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Hauptverfasser: Yilancioglu, Kaan, Weinstein, Zohar B., Meydan, Cem, Akhmetov, Azat, Toprak, Isil, Durmaz, Arda, Iossifov, Ivan, Kazan, Hilal, Roth, Frederick P., Cokol, Murat
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144720/
https://ncbi.nlm.nih.gov/pubmed/25026390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500276x
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