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Diagonal Method to Measure Synergy Among Any Number of Drugs

A synergistic drug combination has a higher efficacy compared to the effects of individual drugs. Checkerboard assays, where drugs are combined in many doses, allow sensitive measurement of drug interactions. However, these assays are costly and do not scale well for measuring interaction among many...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Cokol-Cakmak, Melike, Bakan, Feray, Cetiner, Selim, Cokol, Murat
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101960/
https://ncbi.nlm.nih.gov/pubmed/29985330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57713
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