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Chemogenomics and orthology‐based design of antibiotic combination therapies

Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification of effective combinations highly challenging. Here, we present a computational app...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Syst Biol
Main Authors: Chandrasekaran, Sriram, Cokol‐Cakmak, Melike, Sahin, Nil, Yilancioglu, Kaan, Kazan, Hilal, Collins, James J, Cokol, Murat
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289223/
https://ncbi.nlm.nih.gov/pubmed/27222539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156777
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