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Chemogenomics and orthology‐based design of antibiotic combination therapies

Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification of effective combinations highly challenging. Here, we present a computational app...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Chandrasekaran, Sriram, Cokol‐Cakmak, Melike, Sahin, Nil, Yilancioglu, Kaan, Kazan, Hilal, Collins, James J, Cokol, Murat
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289223/
https://ncbi.nlm.nih.gov/pubmed/27222539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156777
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