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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370231/
https://ncbi.nlm.nih.gov/pubmed/30699106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006774
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