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Prediction of multidimensional drug dose responses based on measurements of drug pairs
Finding potent multidrug combinations against cancer and infections is a pressing therapeutic challenge; however, screening all combinations is difficult because the number of experiments grows exponentially with the number of drugs and doses. To address this, we present a mathematical model that pr...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027409/ https://ncbi.nlm.nih.gov/pubmed/27562164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606301113 |
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