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The incoherent feed-forward loop can generate non-monotonic input functions for genes

Gene regulation networks contain recurring circuit patterns called network motifs. One of the most common network motif is the incoherent type 1 feed-forward loop (I1-FFL), in which an activator controls both gene and repressor of that gene. This motif was shown to act as a pulse generator and respo...

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Autores principales: Kaplan, Shai, Bren, Anat, Dekel, Erez, Alon, Uri
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516365/
https://ncbi.nlm.nih.gov/pubmed/18628744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.43
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