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Prediction of drug cocktail effects when the number of measurements is limited

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

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Podrobná bibliografie
Vydáno v:PLoS Biol
Hlavní autoři: Zimmer, Anat, Tendler, Avichai, Katzir, Itay, Mayo, Avi, Alon, Uri
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675459/
https://ncbi.nlm.nih.gov/pubmed/29073201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002518
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