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Prediction of drug cocktail effects when the number of measurements is limited

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Zimmer, Anat, Tendler, Avichai, Katzir, Itay, Mayo, Avi, Alon, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675459/
https://ncbi.nlm.nih.gov/pubmed/29073201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002518
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