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Prediction of drug cocktail effects when the number of measurements is limited

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

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Bibliografski detalji
Izdano u:PLoS Biol
Glavni autori: Zimmer, Anat, Tendler, Avichai, Katzir, Itay, Mayo, Avi, Alon, Uri
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675459/
https://ncbi.nlm.nih.gov/pubmed/29073201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002518
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