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Noise-precision tradeoff in predicting combinations of mutations and drugs

Many biological problems involve the response to multiple perturbations. Examples include response to combinations of many drugs, and the effects of combinations of many mutations. Such problems have an exponentially large space of combinations, which makes it infeasible to cover the entire space ex...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Tendler, Avichai, Zimmer, Anat, Mayo, Avi, Alon, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548401/
https://ncbi.nlm.nih.gov/pubmed/31116755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006956
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