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Noise-precision tradeoff in predicting combinations of mutations and drugs

Many biological problems involve the response to multiple perturbations. Examples include response to combinations of many drugs, and the effects of combinations of many mutations. Such problems have an exponentially large space of combinations, which makes it infeasible to cover the entire space ex...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Tendler, Avichai, Zimmer, Anat, Mayo, Avi, Alon, Uri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548401/
https://ncbi.nlm.nih.gov/pubmed/31116755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006956
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