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Evolutionary Tradeoffs between Economy and Effectiveness in Biological Homeostasis Systems

Biological regulatory systems face a fundamental tradeoff: they must be effective but at the same time also economical. For example, regulatory systems that are designed to repair damage must be effective in reducing damage, but economical in not making too many repair proteins because making excess...

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Detalhes bibliográficos
Main Authors: Szekely, Pablo, Sheftel, Hila, Mayo, Avi, Alon, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738462/
https://ncbi.nlm.nih.gov/pubmed/23950698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003163
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