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Prediction of drug cocktail effects when the number of measurements is limited

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Zimmer, Anat, Tendler, Avichai, Katzir, Itay, Mayo, Avi, Alon, Uri
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675459/
https://ncbi.nlm.nih.gov/pubmed/29073201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002518
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