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Prediction of drug cocktail effects when the number of measurements is limited

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Biol
Hauptverfasser: Zimmer, Anat, Tendler, Avichai, Katzir, Itay, Mayo, Avi, Alon, Uri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675459/
https://ncbi.nlm.nih.gov/pubmed/29073201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002518
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