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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370231/
https://ncbi.nlm.nih.gov/pubmed/30699106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006774
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