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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370231/
https://ncbi.nlm.nih.gov/pubmed/30699106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006774
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