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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...

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Publicat a:PLoS Comput Biol
Autors principals: Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370231/
https://ncbi.nlm.nih.gov/pubmed/30699106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006774
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