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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370231/
https://ncbi.nlm.nih.gov/pubmed/30699106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006774
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