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Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome

N(6)-methyladenosine (m6A) is the most abundant modified base in eukaryotic mRNA and has been linked to diverse effects on mRNA fate. Current m6A mapping approaches localize m6A residues to 100–200 nt-long regions of transcripts. The precise position of m6A in mRNAs cannot be identified on a transcr...

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Bibliografske podrobnosti
izdano v:Nat Methods
Main Authors: Linder, Bastian, Grozhik, Anya V., Olarerin-George, Anthony O., Meydan, Cem, Mason, Christopher E., Jaffrey, Samie R.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487409/
https://ncbi.nlm.nih.gov/pubmed/26121403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3453
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