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Mapping m6A at individual-nucleotide resolution using crosslinking and immunoprecipitation (miCLIP)
N(6)-methyladenosine (m6A) is the most abundant modified base in eukaryotic mRNA and has been linked to diverse effects on mRNA fate. Current m6A mapping approaches localize m6A residues to 100–200 nt-long regions of transcripts. The precise position of m6A in mRNAs cannot be identified on a transcr...
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| Publicado en: | Methods Mol Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562447/ https://ncbi.nlm.nih.gov/pubmed/28349454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6807-7_5 |
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