Identification of the m(6)Am methyltransferase PCIF1 reveals the location and functions of m(6)Am in the transcriptome

mRNAs are regulated by nucleotide modifications that influence their cellular fate. Two of the most abundant modified nucleotides are N(6)-methyladenosine (m(6)A), found within mRNAs, and N(6),2′-O-dimethyladenosine (m(6)Am), which is found at the first-transcribed nucleotide. Distinguishing these m...

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Foilsithe in:Mol Cell
Main Authors: Boulias, Konstantinos, Toczydłowska-Socha, Diana, Hawley, Ben R., Liberman, Noa, Takashima, Ken, Zaccara, Sara, Guez, Théo, Vasseur, Jean-Jacques, Debart, Françoise, Aravind, L., Jaffrey, Samie R., Greer, Eric Lieberman
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703822/
https://ncbi.nlm.nih.gov/pubmed/31279658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.006
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