Identification of the m(6)Am methyltransferase PCIF1 reveals the location and functions of m(6)Am in the transcriptome

mRNAs are regulated by nucleotide modifications that influence their cellular fate. Two of the most abundant modified nucleotides are N(6)-methyladenosine (m(6)A), found within mRNAs, and N(6),2′-O-dimethyladenosine (m(6)Am), which is found at the first-transcribed nucleotide. Distinguishing these m...

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Publicado en:Mol Cell
Main Authors: Boulias, Konstantinos, Toczydłowska-Socha, Diana, Hawley, Ben R., Liberman, Noa, Takashima, Ken, Zaccara, Sara, Guez, Théo, Vasseur, Jean-Jacques, Debart, Françoise, Aravind, L., Jaffrey, Samie R., Greer, Eric Lieberman
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703822/
https://ncbi.nlm.nih.gov/pubmed/31279658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.006
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