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Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome

N(6)-methyladenosine (m6A) is the most abundant modified base in eukaryotic mRNA and has been linked to diverse effects on mRNA fate. Current m6A mapping approaches localize m6A residues to 100–200 nt-long regions of transcripts. The precise position of m6A in mRNAs cannot be identified on a transcr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Methods
Egile Nagusiak: Linder, Bastian, Grozhik, Anya V., Olarerin-George, Anthony O., Meydan, Cem, Mason, Christopher E., Jaffrey, Samie R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487409/
https://ncbi.nlm.nih.gov/pubmed/26121403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3453
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