A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects

Por Wouters, Bas J., Löwenberg, Bob, Delwel, Ruud
Publicado em 2009

Hypergeometric analysis of tiling-array and sequence data: detection and interpretation of peaks

Por Taskesen, Erdogan, Hoogeboezem, Remco, Delwel, Ruud, Reinders, Marcel JT
Publicado em 2013

Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα

Por Radomska, Hanna S., Alberich-Jordà, Meritxell, Will, Britta, Gonzalez, David, Delwel, Ruud, Tenen, Daniel G.
Publicado em 2012

The Common Viral Insertion Site Evi12 Is Located in the 5′-Noncoding Region of Gnn, a Novel Gene with Enhanced Expression in Two Subclasses of Human Acute Myeloid Leukemia

Por van den Akker, Eric, Vankan-Berkhoudt, Yolanda, Valk, Peter J. M., Löwenberg, Bob, Delwel, Ruud
Publicado em 2005

Retroviral Insertions in Evi12, a Novel Common Virus Integration Site Upstream of Tra1/Grp94, Frequently Coincide with Insertions in the Gene Encoding the Peripheral Cannabinoid Re...

Por Valk, Peter J. M., Vankan, Yolanda, Joosten, Marieke, Jenkins, Nancy A., Copeland, Neal G., Löwenberg, Bob, Delwel, Ruud
Publicado em 1999

A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene

Por Yin, Bin, Delwel, Ruud, Valk, Peter J., Wallace, Margaret R., Loh, Mignon L., Shannon, Kevin M., Largaespada, David A.
Publicado em 2009

Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation

Por Jelier, Rob, Jenster, Guido, Dorssers, Lambert CJ, Wouters, Bas J, Hendriksen, Peter JM, Mons, Barend, Delwel, Ruud, Kors, Jan A
Publicado em 2007

Large-Scale Identification of Disease Genes Involved in Acute Myeloid Leukemia

Por Erkeland, Stefan J., Valkhof, Marijke, Heijmans-Antonissen, Claudia, van Hoven-Beijen, Antoinette, Delwel, Ruud, Hermans, Mirjam H. A., Touw, Ivo P.
Publicado em 2004

Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a fa...

Por Wouters, Bas J., Löwenberg, Bob, Erpelinck-Verschueren, Claudia A. J., van Putten, Wim L. J., Valk, Peter J. M., Delwel, Ruud
Publicado em 2009

HAT: Hypergeometric Analysis of Tiling-arrays with application to promoter-GeneChip data

Por Taskesen, Erdogan, Beekman, Renee, de Ridder, Jeroen, Wouters, Bas J, Peeters, Justine K, Touw, Ivo P, Reinders, Marcel JT, Delwel, Ruud
Publicado em 2010

MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis

Por Yokoyama, Takashi, Nakatake, Mayuka, Kuwata, Takeshi, Couzinet, Arnaud, Goitsuka, Ryo, Tsutsumi, Shuichi, Aburatani, Hiroyuki, Valk, Peter J.M., Delwel, Ruud, Nakamura, Takuro
Publicado no J Clin Invest (2016)

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34(+) cells, allowing nerve growth factor-induced expansion

Por Mulloy, James C., Jankovic, Vladimir, Wunderlich, Mark, Delwel, Ruud, Cammenga, Jorg, Krejci, Ondrej, Zhao, Hui, Valk, Peter J. M., Lowenberg, Bob, Nimer, Stephen D.
Publicado em 2005

HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteristics

Por Verhaak, Roel GW, Sanders, Mathijs A, Bijl, Maarten A, Delwel, Ruud, Horsman, Sebastiaan, Moorhouse, Michael J, van der Spek, Peter J, Löwenberg, Bob, Valk, Peter JM
Publicado em 2006

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

Por Verhaak, Roel G.W., Wouters, Bas J., Erpelinck, Claudia A.J., Abbas, Saman, Beverloo, H. Berna, Lugthart, Sanne, Löwenberg, Bob, Delwel, Ruud, Valk, Peter J.M.
Publicado em 2009

The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation

Por Song, Su Jung, Ito, Keisuke, Ala, Ugo, Kats, Lev, Webster, Kaitlyn, Sun, Suming, Manova-Todorova, Katia, Teruya-Feldstein, Julie, Avigan, David E., Delwel, Ruud, Pandolfi, Pier Paolo
Publicado em 2013

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

Por Lugthart, Sanne, Figueroa, Maria E., Bindels, Eric, Skrabanek, Lucy, Valk, Peter J. M., Li, Yushan, Meyer, Stefan, Erpelinck-Verschueren, Claudia, Greally, John, Löwenberg, Bob, Melnick, Ari, Delwel, Ruud
Publicado em 2011

The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors

Por Liss, Adam, Ooi, Chia-Huey, Zjablovskaja, Polina, Benoukraf, Touati, Radomska, Hanna S., Ju, Chen, Wu, Mengchu, Balastik, Martin, Delwel, Ruud, Brdicka, Tomas, Tan, Patrick, Tenen, Daniel G., Alberich-Jorda, Meritxell
Publicado em 2014

Transcriptional Repression of the Neurofibromatosis-1 Tumor Suppressor by the t(8;21) Fusion Protein

Por Yang, Genyan, Khalaf, Waleed, van de Locht, Louis, Jansen, Joop H., Gao, Meihua, Thompson, Mary Ann, van der Reijden, Bert A., Gutmann, David H., Delwel, Ruud, Clapp, D. Wade, Hiebert, Scott W.
Publicado em 2005

Tribbles homolog 2 (Trib2) inactivates C/EBPalpha and causes acute myelogenous leukemia

Por Keeshan, Karen, He, Yiping, Wouters, Bas J., Shestova, Olga, Xu, Lanwei, Sai, Hong, Rodriguez, Carlos G., Maillard, Ivan, Tobias, John W., Valk, Peter, Carroll, Martin, Aster, Jon C., Delwel, Ruud, Pear, Warren S.
Publicado em 2006

Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways

Por Gröschel, Stefan, Sanders, Mathijs A., Hoogenboezem, Remco, Zeilemaker, Annelieke, Havermans, Marije, Erpelinck, Claudia, Bindels, Eric M. J., Beverloo, H. Berna, Döhner, Hartmut, Löwenberg, Bob, Döhner, Konstanze, Delwel, Ruud, Valk, Peter J. M.
Publicado no Blood (2015)