Tribbles homolog 2 (Trib2) inactivates C/EBPalpha and causes acute myelogenous leukemia

Tribbles homolog 2 (Trib2) was identified as a down-regulated transcript in leukemic cells undergoing growth arrest. To investigate the effects of Trib2 in hematopoietic progenitors, mice were reconstituted with hematopoietic stem cells retrovirally expressing Trib2. Trib2-transduced bone marrow cel...

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Detalhes bibliográficos
Main Authors: Keeshan, Karen, He, Yiping, Wouters, Bas J., Shestova, Olga, Xu, Lanwei, Sai, Hong, Rodriguez, Carlos G., Maillard, Ivan, Tobias, John W., Valk, Peter, Carroll, Martin, Aster, Jon C., Delwel, Ruud, Pear, Warren S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839500/
https://ncbi.nlm.nih.gov/pubmed/17097562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2006.09.012
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