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Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

DNA methylation patterns are frequently dysregulated in cancer, although little is known of the mechanisms through which specific gene sets become aberrantly methylated. The ecotropic viral integration site 1 (EVI1) locus encodes a DNA binding zinc-finger transcription factor that is aberrantly expr...

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Détails bibliographiques
Auteurs principaux: Lugthart, Sanne, Figueroa, Maria E., Bindels, Eric, Skrabanek, Lucy, Valk, Peter J. M., Li, Yushan, Meyer, Stefan, Erpelinck-Verschueren, Claudia, Greally, John, Löwenberg, Bob, Melnick, Ari, Delwel, Ruud
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037746/
https://ncbi.nlm.nih.gov/pubmed/20855866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-281337
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