Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

DNA methylation patterns are frequently dysregulated in cancer, although little is known of the mechanisms through which specific gene sets become aberrantly methylated. The ecotropic viral integration site 1 (EVI1) locus encodes a DNA binding zinc-finger transcription factor that is aberrantly expr...

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Main Authors: Lugthart, Sanne, Figueroa, Maria E., Bindels, Eric, Skrabanek, Lucy, Valk, Peter J. M., Li, Yushan, Meyer, Stefan, Erpelinck-Verschueren, Claudia, Greally, John, Löwenberg, Bob, Melnick, Ari, Delwel, Ruud
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037746/
https://ncbi.nlm.nih.gov/pubmed/20855866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-281337
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