MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

Increasing evidence shows aberrant hypermethylation of genes occurring in and potentially contributing to pathogenesis of myeloid malignancies. Several of these diseases, such as myelodysplastic syndromes (MDSs), are responsive to DNA methyltransferase inhibitors. To determine the extent of promoter...

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Bibliografiska uppgifter
Huvudupphovsmän: Figueroa, Maria E., Skrabanek, Lucy, Li, Yushan, Jiemjit, Anchalee, Fandy, Tamer E., Paietta, Elisabeth, Fernandez, Hugo, Tallman, Martin S., Greally, John M., Carraway, Hetty, Licht, Jonathan D., Gore, Steven D., Melnick, Ari
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2009
Ämnen:
Myeloid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765680/
https://ncbi.nlm.nih.gov/pubmed/19652201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-200519
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