MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

Increasing evidence shows aberrant hypermethylation of genes occurring in and potentially contributing to pathogenesis of myeloid malignancies. Several of these diseases, such as myelodysplastic syndromes (MDSs), are responsive to DNA methyltransferase inhibitors. To determine the extent of promoter...

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Autors principals: Figueroa, Maria E., Skrabanek, Lucy, Li, Yushan, Jiemjit, Anchalee, Fandy, Tamer E., Paietta, Elisabeth, Fernandez, Hugo, Tallman, Martin S., Greally, John M., Carraway, Hetty, Licht, Jonathan D., Gore, Steven D., Melnick, Ari
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765680/
https://ncbi.nlm.nih.gov/pubmed/19652201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-200519
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