MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

Increasing evidence shows aberrant hypermethylation of genes occurring in and potentially contributing to pathogenesis of myeloid malignancies. Several of these diseases, such as myelodysplastic syndromes (MDSs), are responsive to DNA methyltransferase inhibitors. To determine the extent of promoter...

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Détails bibliographiques
Auteurs principaux: Figueroa, Maria E., Skrabanek, Lucy, Li, Yushan, Jiemjit, Anchalee, Fandy, Tamer E., Paietta, Elisabeth, Fernandez, Hugo, Tallman, Martin S., Greally, John M., Carraway, Hetty, Licht, Jonathan D., Gore, Steven D., Melnick, Ari
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765680/
https://ncbi.nlm.nih.gov/pubmed/19652201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-200519
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