Aberrant DNA methylation is a dominant mechanism in MDS progression to AML

Myelodysplastic syndromes (MDSs) are clonal hematologic disorders that frequently represent an intermediate disease stage before progression to acute myeloid leukemia (AML). As such, study of MDS/AML can provide insight into the mechanisms of neoplastic evolution. In 184 patients with MDS and AML, D...

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Main Authors: Jiang, Ying, Dunbar, Andrew, Gondek, Lukasz P., Mohan, Sanjay, Rataul, Manjot, O'Keefe, Christine, Sekeres, Mikkael, Saunthararajah, Yogen, Maciejewski, Jaroslaw P.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Myeloid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637194/
https://ncbi.nlm.nih.gov/pubmed/18832655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-163246
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