FISH and SNP-A karyotyping in myelodysplastic syndromes: improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8, and del(20q)

Cytogenetic aberrations identified by metaphase cytogenetics (MC) have important diagnostic, prognostic and therapeutic roles in myelodysplastic syndromes (MDS). Fluorescence in situ hybridization (FISH) complements MC by the ability to evaluate large numbers of both interphase and metaphase nuclei....

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Detalhes bibliográficos
Main Authors: Makishima, Hideki, Rataul, Manjot, Gondek, Lukasz P., Huh, Jungwon, Cook, James R., Theil, Karl S., Sekeres, Mikkael A., Kuczkowski, Elizabeth, O’Keefe, Christine, Maciejewski, Jaroslaw P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826525/
https://ncbi.nlm.nih.gov/pubmed/19758696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.08.023
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