Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia

Tekijä Shih, Alan H, Meydan, Cem, Shank, Kaitlyn, Garrett-Bakelman, Francine E, Ward, Patrick S, Intlekofer, Andrew, Nazir, Abbas, Stein, Eytan, Knapp, Kristina, Glass, Jacob, Travins, Jeremy, Straley, Kim, Gliser, Camelia, Mason, Chris, Yen, Katharine, Thompson, Craig B, Melnick, Ari, Levine, Ross L
Julkaisussa Cancer Discov (2017)

Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia

Tekijä Brown, Fiona C., Cifani, Paolo, Drill, Esther, He, Jie, Still, Eric, Zhong, Shan, Balasubramanian, Sohail, Pavlick, Dean, Yilmazel, Bahar, Knapp, Kristina M., Alonzo, Todd A., Meshinchi, Soheil, Stone, Richard M., Kornblau, Steven M., Marcucci, Guido, Gamis, Alan S., Byrd, John C., Gonen, Mithat, Levine, Ross L., Kentsis, Alex
Julkaisussa Br J Haematol (2016)

Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms

Tekijä Hobbs, Gabriela S., Hanasoge Somasundara, Amritha Varshini, Kleppe, Maria, Litvin, Rivka, Arcila, Maria, Ahn, Jihae, McKenney, Anna Sophia, Knapp, Kristina, Ptashkin, Ryan, Weinstein, Howard, Heinemann, Murk-Hein, Francis, Jasmine, Chanel, Suzanne, Berman, Ellin, Mauro, Michael, Tallman, Martin S., Heaney, Mark L., Levine, Ross L., Rampal, Raajit K.
Julkaisussa Haematologica (2018)

Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia

Tekijä Coombs, Catherine C., Sallman, David A., Devlin, Sean M., Dixit, Shweta, Mohanty, Abhinita, Knapp, Kristina, Al Ali, Najla H., Lancet, Jeffrey E., List, Alan F., Komrokji, Rami S., Padron, Eric, Arcila, Maria E., Klimek, Virginia M., van den Brink, Marcel R. M., Tallman, Martin S., Levine, Ross L., Rampal, Raajit K., Rapaport, Franck
Julkaisussa Haematologica (2016)

Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias

Tekijä Wang, Kai, Sanchez-Martin, Marta, Wang, Xujun, Knapp, Kristina M., Koche, Richard, Vu, Ly, Nahas, Michelle K., He, Jie, Hadler, Michael, Stein, Eytan M, Tallman, Martin S., Donahue, Amy L, Frampton, Garrett M, Lipson, Doron, Roels, Steven, Stephens, Philip J., Sanford, Eric M, Brennan, Tim, Otto, Geoff A., Yelensky, Roman, Miller, Vincent A., Kharas, Michael G., Levine, Ross L., Ferrando, Adolfo, Armstrong, Scott A., Krivtsov, Andrei V.
Julkaisussa Leukemia (2016)

Integrated DNA/RNA targeted genomic profiling of diffuse large B-cell lymphoma using a clinical assay

Tekijä Intlekofer, Andrew M., Joffe, Erel, Batlevi, Connie L., Hilden, Patrick, He, Jie, Seshan, Venkatraman E., Zelenetz, Andrew D., Palomba, M. Lia, Moskowitz, Craig H., Portlock, Carol, Straus, David J., Noy, Ariela, Horwitz, Steven M., Gerecitano, John F., Moskowitz, Alison, Hamlin, Paul, Matasar, Matthew J, Kumar, Anita, van den Brink, Marcel R., Knapp, Kristina M., Pichardo, Janine D., Nahas, Michelle K., Trabucco, Sally E., Mughal, Tariq, Copeland, Amanda R., Papaemmanuil, Elli, Moarii, Mathai, Levine, Ross L., Dogan, Ahmet, Miller, Vincent A., Younes, Anas
Julkaisussa Blood Cancer J (2018)

Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting

Tekijä He, Jie, Abdel-Wahab, Omar, Nahas, Michelle K., Wang, Kai, Rampal, Raajit K., Intlekofer, Andrew M., Patel, Jay, Krivstov, Andrei, Frampton, Garrett M., Young, Lauren E., Zhong, Shan, Bailey, Mark, White, Jared R., Roels, Steven, Deffenbaugh, Jason, Fichtenholtz, Alex, Brennan, Timothy, Rosenzweig, Mark, Pelak, Kimberly, Knapp, Kristina M., Brennan, Kristina W., Donahue, Amy L., Young, Geneva, Garcia, Lazaro, Beckstrom, Selmira T., Zhao, Mandy, White, Emily, Banning, Vera, Buell, Jamie, Iwanik, Kiel, Ross, Jeffrey S., Morosini, Deborah, Younes, Anas, Hanash, Alan M., Paietta, Elisabeth, Roberts, Kathryn, Mullighan, Charles, Dogan, Ahmet, Armstrong, Scott A., Mughal, Tariq, Vergilio, Jo-Anne, Labrecque, Elaine, Erlich, Rachel, Vietz, Christine, Yelensky, Roman, Stephens, Philip J., Miller, Vincent A., van den Brink, Marcel R. M., Otto, Geoff A., Lipson, Doron, Levine, Ross L.
Julkaisussa Blood (2016)