Genomic Dark Matter Sheds Light on EVI1-driven Leukemia

per Koche, Richard, Armstrong, Scott A.
Publicat 2014

2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation

per Schvartzman, Juan-Manuel, Reuter, Vincent P., Koche, Richard P., Thompson, Craig B.
Publicat a Proc Natl Acad Sci U S A (2019)

HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP

per Sahin, Merve, Wong, Wilfred, Zhan, Yingqian, Van Deynze, Kinsey, Koche, Richard, Leslie, Christina S.
Publicat a Nat Commun (2021)

Arid1a restrains Kras-dependent changes in acinar cell identity

per Livshits, Geulah, Alonso-Curbelo, Direna, Morris, John P, Koche, Richard, Saborowski, Michael, Wilkinson, John Erby, Lowe, Scott W
Publicat a eLife (2018)

Reprogramming factor expression induces rapid and widespread targeted chromatin remodeling

per Koche, Richard P., Smith, Zachary D., Adli, Mazhar, Gu, Hongcang, Ku, Manching, Gnirke, Andreas, Bernstein, Bradley E., Meissner, Alexander
Publicat 2011

The MicrobesOnline Web site for comparative genomics

per Alm, Eric J., Huang, Katherine H., Price, Morgan N., Koche, Richard P., Keller, Keith, Dubchak, Inna L., Arkin, Adam P.
Publicat 2005

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells

per Mendenhall, Eric M., Koche, Richard P., Truong, Thanh, Zhou, Vicky W., Issac, Biju, Chi, Andrew S., Ku, Manching, Bernstein, Bradley E.
Publicat 2010

H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

per Ku, Manching, Jaffe, Jacob D, Koche, Richard P, Rheinbay, Esther, Endoh, Mitsuhiro, Koseki, Haruhiko, Carr, Steven A, Bernstein, Bradley E
Publicat 2012

DICER1 Is Essential for Self-Renewal of Human Embryonic Stem Cells

per Teijeiro, Virginia, Yang, Dapeng, Majumdar, Sonali, González, Federico, Rickert, Robert W., Xu, Chunlong, Koche, Richard, Verma, Nipun, Lai, Eric C., Huangfu, Danwei
Publicat a Stem Cell Reports (2018)

A non-catalytic function of SETD1A regulates Cyclin-K and the DNA damage response

per Hoshii, Takayuki, Cifani, Paolo, Feng, Zhaohui, Huang, Chun-Hao, Koche, Richard, Chen, Chun-Wei, Delaney, Christopher D., Lowe, Scott W., Kentsis, Alex, Armstrong, Scott A.
Publicat a Cell (2018)

MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells

per Müller, Iris, Moroni, Ann Sophie, Shlyueva, Daria, Sahadevan, Sudeep, Schoof, Erwin M., Radzisheuskaya, Aliaksandra, Højfeldt, Jonas W., Tatar, Tülin, Koche, Richard P., Huang, Chang, Helin, Kristian
Publicat a Nat Commun (2021)

Hematopoietic differentiation is required for initiation of acute myeloid leukemia

per Ye, Min, Zhang, Hong, Yang, Henry, Koche, Richard, Staber, Philipp B., Cusan, Monica, Levantini, Elena, Welner, Robert S., Bach, Christian S., Zhang, Junyan, Krivtsov, Andrei, Armstrong, Scott A., Tenen, Daniel G.
Publicat a Cell Stem Cell (2015)

Forward genetic screen of human transposase genomic rearrangements

per Henssen, Anton G., Jiang, Eileen, Zhuang, Jiali, Pinello, Luca, Socci, Nicholas D., Koche, Richard, Gonen, Mithat, Villasante, Camila M., Armstrong, Scott A., Bauer, Daniel E., Weng, Zhiping, Kentsis, Alex
Publicat a BMC Genomics (2016)

A UTX–MLL4–p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription

per Wang, Shu-Ping, Tang, Zhanyun, Chen, Chun-Wei, Shimada, Miho, Koche, Richard P., Wang, Lan-Hsin, Nakadai, Tomoyoshi, Chramiec, Alan, Krivtsov, Andrei V., Armstrong, Scott A., Roeder, Robert G.
Publicat a Mol Cell (2017)

Peptidomimetic blockade of MYB in acute myeloid leukemia

per Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex
Publicat a Nat Commun (2018)

MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition

per Kühn, Michael W.M., Hadler, Michael J., Daigle, Scott R., Koche, Richard P., Krivtsov, Andrei V., Olhava, Edward J., Caligiuri, Michael A., Huang, Gang, Bradner, James E., Pollock, Roy M., Armstrong, Scott A.
Publicat a Haematologica (2015)

NUP98-Fusion Proteins Interact With the NSL and MLL1 Complexes To Drive Leukemogenesis

per Xu, Haiming, Valerio, Daria G, Eisold, Meghan E, Sinha, Amit, Koche, Richard P, Hu, Wenhuo, Chen, Chun-Wei, Chu, S Haihua, Brien, Gerard L, Park, Christopher Y., Hsieh, James J., Ernst, Patricia, Armstrong, Scott A
Publicat a Cancer Cell (2016)

Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity

per Finley, Lydia W.S., Vardhana, Santosha A., Carey, Bryce W., Alonso-Curbelo, Direna, Koche, Richard, Chen, Yanyang, Wen, Duancheng, King, Bryan, Radler, Megan R., Rafii, Shahin, Lowe, Scott W., Allis, C. David, Thompson, Craig B.
Publicat a Nat Cell Biol (2018)

Inhibition of MEK and ATR is effective in a B-cell acute lymphoblastic leukemia model driven by Mll-Af4 and activated Ras

per Chu, S. Haihua, Song, Evelyn J., Chabon, Jonathan R., Minehart, Janna, Matovina, Chloe N., Makofske, Jessica L., Frank, Elizabeth S., Ross, Kenneth, Koche, Richard P., Feng, Zhaohui, Xu, Haiming, Krivtsov, Andrei, Nussenzweig, Andre, Armstrong, Scott A.
Publicat a Blood Adv (2018)

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

per Takao, Sumiko, Forbes, Lauren, Uni, Masahiro, Cheng, Shuyuan, Pineda, Jose Mario Bello, Tarumoto, Yusuke, Cifani, Paolo, Minuesa, Gerard, Chen, Celine, Kharas, Michael G, Bradley, Robert K, Vakoc, Christopher R, Koche, Richard P, Kentsis, Alex
Publicat a eLife (2021)