H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

BACKGROUND: The histone variant H2A.Z has been implicated in nucleosome exchange, transcriptional activation and Polycomb repression. However, the relationships among these seemingly disparate functions remain obscure. RESULTS: We mapped H2A.Z genome-wide in mammalian ES cells and neural progenitors...

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Detalhes bibliográficos
Main Authors: Ku, Manching, Jaffe, Jacob D, Koche, Richard P, Rheinbay, Esther, Endoh, Mitsuhiro, Koseki, Haruhiko, Carr, Steven A, Bernstein, Bradley E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491413/
https://ncbi.nlm.nih.gov/pubmed/23034477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-r85
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