GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells

Polycomb proteins are epigenetic regulators that localize to developmental loci in the early embryo where they mediate lineage-specific gene repression. In Drosophila, these repressors are recruited to sequence elements by DNA binding proteins associated with Polycomb repressive complex 2 (PRC2). Ho...

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Detalhes bibliográficos
Main Authors: Mendenhall, Eric M., Koche, Richard P., Truong, Thanh, Zhou, Vicky W., Issac, Biju, Chi, Andrew S., Ku, Manching, Bernstein, Bradley E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000368/
https://ncbi.nlm.nih.gov/pubmed/21170310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001244
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