Interdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements

Polycomb Group (PcG) proteins are epigenetic repressors essential for control of development and cell differentiation. They form multiple complexes of which PRC1 and PRC2 are evolutionary conserved and obligatory for repression. The targeting of PRC1 and PRC2 is poorly understood and was proposed to...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kahn, Tatyana G., Dorafshan, Eshagh, Schultheis, Dorothea, Zare, Aman, Stenberg, Per, Reim, Ingolf, Pirrotta, Vincenzo, Schwartz, Yuri B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137424/
https://ncbi.nlm.nih.gov/pubmed/27557709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw701
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