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Jarid2 and PRC2, partners in regulating gene expression

The Polycomb group proteins foster gene repression profiles required for proper development and unimpaired adulthood, and comprise the components of the Polycomb-Repressive Complex 2 (PRC2) including the histone H3 Lys 27 (H3K27) methyltransferase Ezh2. How mammalian PRC2 accesses chromatin is uncle...

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Autors principals: Li, Gang, Margueron, Raphael, Ku, Manching, Chambon, Pierre, Bernstein, Bradley E., Reinberg, Danny
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816736/
https://ncbi.nlm.nih.gov/pubmed/20123894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1886410
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