DICER1 Is Essential for Self-Renewal of Human Embryonic Stem Cells

MicroRNAs (miRNAs) are the effectors of a conserved gene-silencing system with broad roles in post-transcriptional regulation. Due to functional overlaps, assigning specific functions to individual miRNAs has been challenging. DICER1 cleaves pre-miRNA hairpins into mature miRNAs, and previously Dice...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Teijeiro, Virginia, Yang, Dapeng, Majumdar, Sonali, González, Federico, Rickert, Robert W., Xu, Chunlong, Koche, Richard, Verma, Nipun, Lai, Eric C., Huangfu, Danwei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135725/
https://ncbi.nlm.nih.gov/pubmed/30146489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.07.013
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